Modafinil; Uses, Dosage, Side Effects, Interactions

Modafinil

Modafinil is a synthetic central nervous system stimulant with wakefulness-promoting activity. Modafinil appears to inhibit dopamine reuptake, resulting in an increase in extracellular dopamine. This agent exhibits pronounced wakefulness-promoting activity (without sympathomimetic activity) and may improve cognitive function in certain clinical settings. (NCI04) Modafinil and its R-enantiomer armodafinil are Read More …

Desvenlafaxine; Uses, Dosage, Side Effects, Interactions

desvenlafaxine

Desvenlafaxine is a synthetic phenethylamine bicyclic derivative with antidepressant activity. Desvenlafaxine is a selective reuptake inhibitor of serotonin and norepinephrine due to its high binding affinities to the pre-synaptic serotonin and norepinephrine transporters. By blocking both transporters, this agent prolongs neurotransmitter activities of both serotonin and norepinephrine, thereby alleviating depressive state. O-Desmethylvenlafaxine is a metabolite of Venlafaxine. Desvenlafaxine (brand name: Read More …

Venlafaxine; Uses, Dosage, Side Effects, Interactions

Venlafaxine is a synthetic phenethylamine bicyclic derivative with antidepressant activity. Venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), are potent inhibitors of neuronal serotonin and norepinephrine reuptake and weak dopamine reuptake inhibitors. This agent may reduce hormone-related vasomotor symptoms. (NCI04) Venlafaxine is a serotonin and norepinephrine reuptake inhibitor widely used as an antidepressant. Venlafaxine therapy can be associated with transient asymptomatic Read More …

Podophyllin; Uses, Dosage, Site Effects, Interactions

Podophyllin

Podophyllin is a resin extracted from the root of the plant Podophyllum sp. Berberidaceae (Mandrake), which contains numerous compounds, among which podophyllotoxin. Podophyllin is the principal active component. Podophyllin arrests mitosis in metaphase. Caustic extract from the roots of Podophyllum peltatum and P. emodi. Podophyllum resin Read More …

Norfloxacin; Uses, Dosage, Side Effects, Interactions, Pregnan

Norfloxacin

Norfloxacin is a synthetic, broad-spectrum fluoroquinolone with antibacterial activity. Norfloxacin inhibits the activity of DNA gyrase, thereby blocking bacterial DNA replication. Norfloxacin concentrates in the renal tubules and bladder and is bactericidal against a wide range of aerobic gram-positive and gram-negative organisms. Norfloxacin is a synthetic fluoroquinolone Read More …