Cefpimizole; Uses, Dosage, Side effects, Interactions

Cefpimizole








User Review


5
(1 vote)


Cefpimizole is a semisynthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity. Cefpimizole binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

Mechanism of Action of Cefpimizole

The bactericidal activity of cefpimizole results from the inhibition of cell wall synthesis via affinity for penicillin-binding proteins (PBPs). Cefpimizole is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. Cefpimizole Sodium is the sodium salt form of cefpimizole, a semisynthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity. Cefpimizole binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

Pharmacology of Cefpimizole

Cefpimizole is a semisynthetic, broad-spectrum, third-generation cephalosporin with antibacterial activity. Cefpimizolebinds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

…………….data or information not available. For further information 

https://pubchem.ncbi.nlm.nih.gov/compound/cefpimizole_sodium

You Can Also Like   Ribociclib; Uses, Dosage, Side Effects, Interactions

References

Cefpimizole

Print Friendly, PDF & Email

Sharing to Spread to the World

Leave a Reply

Your email address will not be published.