Fimasartan; Uses, Dosage, Side Effects, Interactions, Pregnan

Fimasartan

Fimasartan is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administration of fimasartan with diuretic hydrochlorothiazide has shown to be safe in clinical trials. Fimasartan was approved for use in South Korea on September 9th, 2010 and is available under the brand name Kanarb through Boryung Pharmaceuticals, who are presently seeking worldwide partnership. Mechanism of Action of Fimasartan Angiotensin II activates Read More …

Spironolactone; Uses, Dosage, Side Effects, Drug Interactions

spirolactone

Spironolactone is a potassium-sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. It is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are utilized in the treatments of hirsutism and acne but they can lead to adverse effects. Spironolactone is Read More …

Hydrochlorothiazide; Uses, Dosage, Side Effects, Interactions

Hydrochlorothiazide is a thiazide diuretic often considered the prototypical member of this class. It reduces the reabsorption of electrolytes from the renal tubules. This results in increased excretion of water and electrolytes, including sodium, potassium, chloride, and magnesium. It is used in the treatment of several disorders including edema, hypertension, diabetes insipidus, and hypoparathyroidism. Hydrochlorothiazide is a diuretic medication often used to treat high Read More …

Furosemide; Uses, Dosage, Side Effects, Interactions, Pregnan

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Furosemide is a sulfamoyl anthranilic acid derivative, also known as frusemide, and a potent loop diuretic. Furosemide is widely used to treat hypertension and edema. This agent is highly bound to albumin and is largely excreted unchanged in the urine. Furosemide belongs to the class of medications called loops diuretics. It is used to treat edema (fluid retention) that occurs with congestive heart failure and disorders of Read More …

Diuretic; Uses, Types, Side Effects, Drug Interactions

Diuretic

Diuretic is any substance that promotes diuresis, that is, the increased production of urine. This includes forced diuresis. There are several categories of diuretics. All diuretics increase the excretion of water from bodies, although each class does so in a distinct way. Alternatively, an antidiuretic such as vasopressin (antidiuretic hormone), is an agent or drug which reduces the excretion of water in urine. Medical Uses of Diuretic In medicine, diuretics are used Read More …

Iron /Ferric Carboxymaltose; Uses, Dosage, Side Effects

Iron /Ferric Carboxymaltose

Iron /Ferric Carboxymaltose /Iron (III)-hydroxide polymaltose complex is a medication used to treat iron deficiency/iron deficiency anemia and belongs to the group of oral iron preparations. The preparation is a macromolecular complex, consisting of iron(III)-hydroxide (trivalent iron, Fe3+) and the carrier polymaltose and is available in solid form as a film-coated or chewable tablet and in liquid form as a syrup, drinkable solution, Read More …

Iron Dextran; Uses, Dosage, Side Effects, Interactions

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Iron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. Iron Dextran is used for the treatment of patients with documented iron deficiency in which oral administration is unsatisfactory or impossible. Iron dextran is a form of the mineral iron. Iron is important for many functions in the body, especially for the transport of oxygen in the blood. Iron dextran is Read More …

Iron Sucrose; Uses, Dosage, Side effects, Interactions

Iron Sucrose

Iron Sucrose/Iron saccharate (Sucroferric oxyhydroxide or Iron Sucrose) is used as a source of iron in patients with iron deficiency anemia with chronic kidney disease (CKD), including those who are undergoing dialysis (hemodialysis or peritoneal) and those who do not require dialysis. Due to fewer side effects than iron dextran, iron saccharate is more preferred in chronic kidney disease patients. Iron sucrose is an intravenously administered iron product indicated in the treatment Read More …

Trimethoprim; Uses, Dosage, Side Effects, Interactions

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Trimethoprim is a synthetic derivative of trimethoxybenzyl-pyrimidine with antibacterial and antiprotozoal properties. As a pyrimidine inhibitor of bacterial dihydrofolate reductase, trimethoprim binds tightly to the bacterial enzyme, blocking the production of tetrahydrofolic acid from dihydrofolic acid. The antibacterial activity of this agent is potentiated by sulfonamides Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections. Other uses include for middle ear infections and travelers’ diarrhea. A pyrimidine inhibitor of dihydrofolate reductase, it is Read More …

Nateglinide; Uses, Dosage, Side Effects, Interactions

Nateglinide is a phenylalanine derivative of the meglitinide class of agents with hypoglycemic activity. Nateglinide, compared to repaglinide, binds with a higher affinity to the SUR1 subunit and with a faster onset of action and a shorter duration of action. This agent is metabolized by the cytochrome P450 isoenzyme CYP2C9, and, to a lesser extent, by CYP3A4. The parent drug and metabolites are mainly excreted in Read More …

Repaglinide;Uses, Dosage, Side Effects, Drug Interactions

Repaglinide

Repaglinide is a nonsulfonylurea insulin secretagogue belonging to the melgitinide class with hypoglycemic activity. Repaglinide is rapidly absorbed and has a rapid onset and short duration of action. This agent is metabolized in the liver by CYP2C8 and CYP3A4 and its metabolites are excreted in the bile. Repaglinide has a half-life of one hour. Repaglinide is a benzoic acid derivative that stimulates insulin secretion from the pancreas and Read More …

Empagliflozin; Uses, Dosage, Side Effects, Drug Interactions

Cefdaloxime Antibiotic

Empagliflozin is a drug of the gliflozin class, approved for the treatment of type 2 diabetes in adults in 2014. Empagliflozin is a sodium glucose co-transporter-2 (SGLT-2) inhibitor indicated as an adjunct to diet and exercise to improve glycemic control in adult patients with type 2 diabetes. SGLT2 co-transporters are responsible for reabsorption of glucose from the glomerular filtrate in the kidney. The glucuronic effect resulting Read More …

Dapagliflozin; Uses, Dosage, Side Effects, Drug Interactions

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Dapagliflozin is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity. Dapagliflozin selectively and potently inhibits SGLT2 compared to SGLT1, which is the cotransporter of glucose in the gut. Dapagliflozin is a Sodium-Glucose Cotransporter 2 Inhibitor. The mechanism of action of dapagliflozin is as a Sodium-Glucose Transporter 2 Inhibitor. Dapagliflozin is indicated for the management of diabetes mellitus type 2, and functions to improve glycemic control Read More …

Canagliflozin; Uses, Dosage, Side Effects, Drug Interactions

Canagliflozin anhydrous is a Sodium-Glucose Cotransporter 2 Inhibitor. The mechanism of action of canagliflozin anhydrous is as a Sodium-Glucose Transporter 2 Inhibitor and P-Glycoprotein Inhibitor. Canagliflozin Anhydrous is the anhydrous form of canagliflozin, a C-glucoside with a thiophene ring that is an orally available inhibitor of sodium-glucose transporter 2 (SGLT2) with antihyperglycemic activity. Canagliflozin is also able to reduce body weight and has a low risk for hypoglycemia. Canagliflozin Read More …

Teneligliptin Drug; Mechanism, Uses, Dosage, Side effects, Interaction

Teneligliptin Drug

Teneligliptin is a long-acting, orally bioavailable, pyrrolidine-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Teneligliptin may also reduce plasma triglyceride levels through a sustained increase in GLP-1 levels. Teneligliptin has been investigated for the treatment of Type 2 Diabetes Mellitus Teneligliptin is an antidiabetic medicine used in the treatment of type 2 diabetes in adult patients. Patients are advised to follow a strict Read More …